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Combigan Eye Drop (Timolol 5mg / Brimonidine 2mg)

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Product Description

Combigan Ophthalmic Solution 5ml

Combigan Ophthalmic Solution 5ml is a combination medicine indicated for lowering the elevated intraocular pressure in patients with glaucoma or ocular hypertension. Glaucoma is an eye disease that causes damage to the optic nerve and results in reduced vision. Ocular hypertension is increased pressure in the eye due to poor drainage of aqueous humour (fluid in the eye that maintains normal pressure by its continuous flow).

Combigan Ophthalmic Solution 5ml is a combination of three drugs, namely: Brimonidine tartrate (alpha-2 adrenergic receptor agonists), Timolol (beta-blocker), and Benzalkonium chloride (preservative). Brimonidine tartrate and timolol decrease the production of aqueous humour and increase the amount of fluid that is drained. Benzalkonium chloride acts as a preservative. Together, Combigan Ophthalmic Solution 5ml helps lower the increased pressure in the eye.

Combigan Ophthalmic Solution 5ml is for ophthalmic only. You are advised to use Combigan Ophthalmic Solution 5ml for as long as your doctor has prescribed it for you, depending on your medical condition. In some cases, you may experience certain common side effects such as burning sensation, eye redness, itching, irritation, and vision disturbances. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.

Consult a doctor before using Combigan Ophthalmic Solution 5ml if you are pregnant or breastfeeding. Combigan Ophthalmic Solution 5ml is not recommended for children below 17years as the safety and effectiveness have not been established. Combigan Ophthalmic Solution 5ml might cause drowsiness; so, drive only if you are alert. Avoid touching the tip of the dropper as it may contaminate the contents. Keep your doctor informed about your health condition and the medicines you are taking to prevent any side effects/interactions.

Uses of Combigan Ophthalmic Solution 5ml

Glaucoma and ocular hypertension

Medicinal Benefits

Combigan Ophthalmic Solution 5ml is a combination of three drugs, namely: Brimonidine tartrate, Timolol, and Benzalkonium chloride. Combigan Ophthalmic Solution 5ml is indicated for lowering intraocular pressure in patients with glaucoma or ocular hypertension. Brimonidine tartrate belongs to a group of medicines called alpha-2 adrenergic receptor agonists and Timolol belongs to the group of medicines called beta-blockers. They work by decreasing the production of aqueous humour and increase the amount of liquid that is drained. Benzalkonium chloride acts as a preservative. Together, Combigan Ophthalmic Solution 5ml helps lower the increased pressure in the eye.

Directions for Use

Combigan Ophthalmic Solution 5ml is for ophthalmic use only. Wash your hands before and after use. Shake the bottle well before each use. Instil the eye drops by pulling down the lower eyelid to form a pocket between eyelid and eye. Do not touch the tip of the dropper as it may contaminate the solution. Depending on your condition, your doctor will decide how long you need to use Combigan Ophthalmic Solution 5ml.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Combigan Ophthalmic Solution 5ml

  • Burning sensation
  • Eye redness
  • Eye itching
  • Irritation
  • Vision disturbances

In-Depth Precautions and Warning

Drug Warnings

Do not use Combigan Ophthalmic Solution 5ml if you are allergic to any of its contents if you have/had bronchial asthma, severe chronic obstructive bronchitis, low heart rate, heartbeat disorder, heart failure if you are taking anti-depressants or monoamine oxidase inhibitors. Inform your doctor before taking Combigan Ophthalmic Solution 5ml if you have/had coronary heart disease, slow heartbeat, breathing problems, chronic obstructive pulmonary disease, poor blood circulation disease, diabetes, overactive thyroid, tumour of the adrenal gland, corneal disease, excess acidity in the blood, kidney or liver problems. If you are due to have any surgery or eye surgery, inform the doctor/surgeon that you are taking Combigan Ophthalmic Solution 5ml. Consult a doctor before using Combigan Ophthalmic Solution 5ml if you are pregnant or breastfeeding. Combigan Ophthalmic Solution 5ml is not recommended for children below 17years. Combigan Ophthalmic Solution 5ml might cause drowsiness, and blurred vision; so, drive only if you are alert.

Drug Interactions

Drug-Drug Interactions: Combigan Ophthalmic Solution 5ml may have interaction with anti-arrhythmic agents (digitalis, quinidine), anti-depressants (fluoxetine, paroxetine), antipsychotics (chlorpromazine). Inform your doctor if you are taking pain killers, medicines used to treat anxiety, anti-hypertensives, anti-diabetics, antacids, or anti-glaucoma agents.

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